Postdoctoral Research Fellow - IMM - Center for Translational Cancer Research
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- McGovern Medical School at UTHealth Houston
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- 240003DQ Requisition #
Institute of Molecule Medicine - Proteolysis targeted cancer drug discovery
Postdoctoral Research Fellow Position in Cancer Drug Discovery
A postdoctoral position is available to discover novel protein-based therapeutics for cancer treatment in the laboratory, Center for Translational Cancer Research, Brown Foundation Institute of Molecular Medicine. The laboratory is focused on understanding the function and mechanism of LGR4/5/6 (leucine-rich repeat-containing, G protein-coupled receptor 4, 5, and 6) in Wnt signaling and targeting the three receptors for cancer treatment. LGR4/5/6 are abundantly expressed in gastrointestinal cancer with LGR5 being a marker of cancer stem cells/tumor-initiating cells. Our lab is using multiple approaches that target LGR4/5/6 for the treatment of gastrointestinal cancer, including drug conjugates of modified ligands and proteolysis targeting of oncogenes. The postdoctoral position will focus on the creation and characterization of bi-specific molecules that target oncogenic driver genes and immune modulators for degradation using cutting edge technology of drug discovery.
Minimum Requirements:
A Ph.D. in the field of biochemistry, cell biology, cancer biology, pharmacology, or therapeutics.
Description of Qualified Candidates:
Experience with molecular cloning, protein purification, cancer cell line culturing, and xenograft cancer models are highly desirable but not required.
What we do here changes the world. UTHealth Houston is Texas’ resource for healthcare education, innovation, scientific discovery, and excellence in patient care. That’s where you come in.
Once you join us you won't want to leave. It’s because we reward our team for the excellent service they provide. Our total rewards package includes the benefits you’d expect from a top healthcare organization (benefits, insurance, etc.), plus:
- 100% paid medical premiums for our full-time employees
- Generous time off (holidays, preventative leave day, both vacation and sick time – all of which equates to around 37-38 days per year)
- The longer you stay, the more vacation you’ll accrue!
- Longevity Pay (Monthly payments after two years of service)
- Build your future with our awesome retirement/pension plan!
We take care of our employees! As a world-renowned institution, our employees’ wellbeing is important to us. We offer work/life services such as...
- Free financial and legal counseling
- Free mental health counseling services
- Gym membership discounts and access to wellness programs
- Other employee discounts including entertainment, car rentals, cell phones, etc.
- Resources for child and elder care
- Plus many more!
Position Summary:
A postdoc position provides an opportunity for early-career researchers to gain valuable experience, develop independent research skills, and contribute to the advancement of scientific knowledge in their field of expertise.
Minimum Education:
Doctoral/Terminal Degree
Prefer a Ph.D. in the field of biochemistry, cell biology, cancer biology, pharmacology, or therapeutics.
Physical Requirements:
Exerts up to 20 pounds of force occasionally and/or up to 10 pounds frequently and/or a negligible amount constantly to move objects.
Security Sensitive:
This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code § 51.215
Residency Requirement:
Employees must permanently reside and work in the State of Texas.
If you are looking for a great healthcare career in Houston, visit http://go.uth.edu/careers!
University of Texas Health Science Center at Houston (UTHealth)
Established in 1972 by The University of Texas System Board of Regents, The University of Texas Health Science Center at Houston (UTHealth) is Houston’s Health University and Texas’ resource for health care education, innovation, scientific discovery and excellence in patient care. The most comprehensive academic health center in the UT System and the U.S. Gulf Coast region, UTHealth Houston is home to schools of biomedical informatics, biomedical sciences, dentistry, nursing and public health and the John P. and Kathrine G. McGovern Medical School. UTHealth Houston includes The University of Texas Harris County Psychiatric Center, as well as the growing clinical practices UT Physicians, UT Dentists and UT Health Services. The university’s primary teaching hospitals are Memorial Hermann-Texas Medical Center, Children’s Memorial Hermann Hospital and Harris Health Lyndon B. Johnson Hospital.
UTHealth Benefits
UTHealth Houston offers a comprehensive and competitive benefits package. For more information on our benefits programs please refer to the UTHealth Houston Office of Benefits Website.
Equal Employment Opportunity Statement
UTHealth Houston is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth Houston policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.
UTHealth Houston has adopted a policy consistent with CMS regulations to protect our patients and university community from exposure to COVID-19. This policy affects all employees, residents, fellows, students, contractors, new hires, visiting scholars program participants, adjunct faculty, and volunteers who work, train, or collaborate at the John S. Dunn Behavioral Science Center.
In addition, all UTHealth Houston employees who are assigned to work at a location that is subject to the affiliated partner’s hospital, clinical offices, or agency are required to abide by UTHealth’s Houston rules and regulations, as well as the affiliate’s rules and regulations, including COVID-19 vaccination and safety requirements.
Work location is based on the needs of the department and may be adjusted.
